- Super Pilot
- Super High Ball: Pinball Platformer
- Super Galaxy Squadron
- Super Buckyball Tournament
- Sunday Gold
- Summer Athletics
- Sui Generis
- Sugar Cube: Bittersweet Factory
- Sudden Attack
- Succubus
- Substream
- Subsiege
- Subject A-119
- Stuntfest: World Tour
- Stronghold Legends
- Stronghold Crusader Extreme
- Stronghold Crusader 2
- Strong Bad's Cool Game for Attractive People: Episode 3 - Baddest of the Bands
- Stroke of Fate: Operation Valkyrie, A
- Strike Vector
- Strength of the Sword: Ultimate
- Street Racer Europe
- Street Gears
- Street Fighter x Mega Man
- Strategic Command World War I: The Great War 1914-1918
- Strategic Command 2: Patton Drives East
- Strangeland
- Strange Horticulture
- Strange Cases: The Tarot Card Mystery
- Strange Cases: The Lighthouse Mystery
- Strange Attractors 2
- Story About My Uncle, A
- Stormgate
- Stormdivers
- Storm: Frontline Nation
- Stonehearth
- StoneAge 2
- Stomping Land, The
- Stirring Abyss
- Stick It to the Stickman
- Stellar Tactics
- Stellar Impact
- Steel Storm: A.M.M.O.
- Steel Legions
- Steel Division 2
- Steel Armor: Blaze of War
- SteamWorld Headhunter
- Stay Out
- Stay Dead Evolution
- Stasis: Bone Totem
- Starship Troopers: Terran Command
- Starship Troopers: Extermination
- Stars in Shadow: Legacies
- Starpoint Gemini: Warlords - Rise of Numibia
- Starpoint Gemini: Warlords
- Starpoint Gemini 2: Secrets of Aethera
- Starpoint Gemini 2
- Starpoint Gemini
- Stargate: Timekeepers
- Stargate Resistance
- Starfall Online
- StarDrive
- Star Wolves 3: Civil War
- Star Wars: The Old Republic
- Star Wars: Empire at War - Forces of Corruption
- Star Wars: Clone Wars Adventures
- Star Wars: Attack Squadrons
- Star-Twine
- Star Ruler
- Star Quest 2: United Galaxies
- Star Dynasties
- Star Control: Origins
- Star Citizen
- Star Alliances
- Stalin vs. Martians
- Stalin Subway: Red Veil, The
- Stalin Subway, The
- Squad
- SpyParty
- Spooky Spirits
- Splatter
- Spirit Tales
- Spiral Knights
- Spintires
- Spintires: SHERP Ural Challenge
- Spintires: Chernobyl
- Spiderwick Chronicles, The
- Spider-Man: Web of Shadows
- Spice Road
- Sphere: Flying Cities
- Sphere 3: Enchanted World
- Spellweaver
- SpellMaster: The Saga
- SpellForce 2: Faith in Destiny
- SpellForce 2: Demons of the Past
- Space War Commander
- Space Siege
- Space Shock
- Space Run
- Space Rangers 2: Rise of the Dominators