- Servo
- Settlers 2, The
- Settlers 7: Paths to a Kingdom, The
- SEUM: Speedrunners from Hell
- Seven Dragon Saga
- SGS NATO's Nightmare
- SGS Operation Downfall
- Shadow Blade
- Shadow Blade: Reload
- Shadow Man
- Shadow of a Soul: Chapter 1
- Shadow of the Tomb Raider
- Shadow of the Tomb Raider: The Forge
- Shadow of the Tomb Raider: The Grand Caiman
- Shadow of the Tomb Raider: The Path Home
- Shadow of the Tomb Raider: The Pillar
- Shadow of the Tomb Raider: The Price of Survival
- Shadow of the Tomb Raider: The Serpent's Heart
- Shadow Tactics: Blades of the Shogun
- Shadow Warrior [I/1997]
- Shadow Wolf Mysteries: Bane of the Family
- Shadow Wolf Mysteries: Curse of the Full Moon
- Shadowgate [II/2014]
- Shadowgun: Deadzone
- Shadowrun Chronicles: Boston Lockdown
- Shadowrun: Dragonfall
- Shadowrun: Dragonfall - Director's Cut
- Shadowrun: Hong Kong
- Shadowrun Returns
- Shadows of Adam
- Shadows of Kurgansk
- Shadows Over Loathing
- Shadwen
- Shallow Space
- Shank
- Shantae and the Seven Sirens
- Shapeshifting Detective, The
- Shatter
- Shattered Steel
- She Dreams Elsewhere
- She Sees Red
- Sheba: A New Dawn
- ShellShock Live
- Shelter
- Shelter 2
- Shelter 3
- Sheltered
- Shenzhen I/O
- Shift Orb
- Shiness: The Lightning Kingdom
- Shing!
- Shiny the Firefly
- Ship: Remasted, The
- Ships N' Battles
- Shock Tactics
- Shooting Stars!
- Shopkeeper, The
- Short Hike, A
- Shovel Knight
- Shovel Knight: Dig
- Shovel Knight: King of Cards
- Shovel Knight: Showdown
- Shovel Knight: Specter of Torment
- Showdown Effect, The
- Shroud of the Avatar: Forsaken Virtues
- Shrouded Isle, The
- Shufflepuck Cantina
- Shutter Island
- SickBrick
- Sid Meier's Alpha Centauri
- Sid Meier's Alpha Centauri: Alien Crossfire
- Sid Meier's Civilization
- Sid Meier's Civilization 2
- Sid Meier's Civilization 3
- Sid Meier's Civilization 4
- Sid Meier's Civilization 5
- Sid Meier's Civilization 5: Brave New World
- Sid Meier's Civilization 5: Gods & Kings
- Sid Meier's Civilization 6
- Sid Meier's Civilization 6: Babylon Pack
- Sid Meier's Civilization 6: Byzantium & Gaul Pack
- Sid Meier's Civilization 6: Ethiopia Pack
- Sid Meier's Civilization 6: Gathering Storm
- Sid Meier's Civilization 6: Maya & Gran Colombia Pack
- Sid Meier's Civilization 6: Rise and Fall
- Sid Meier's Civilization: Beyond Earth
- Sid Meier's Civilization: Beyond Earth - Rising Tide
- Sid Meier's Pirates! [I/1987]
- Sid Meier's Pirates! [II/2004]
- Sid Meier's Railroad Tycoon
- Sid Meier's Railroads!
- Sid Meier's Starships
- Side Effect
- Siegecraft Commander
- Sigma Theory: Global Cold War
- Sigma Theory: Global Cold War - Nigeria
- Sign Motion
- Signal from Tölva, The
- Signal Ops
- Signifier, The